=============== Getting started =============== Default Configurations ----------------------- *optimModels*, at the moment supports kinetic metabolic models, communities models and Gecko models. The default configurations used in the optimization/simulation processes are in the optimModels.utils.configuration file. The parameters of EA can be changed using the class optimModels.optimization.evolutionary_algorithm.EAConfigurations Loading kinetic models ----------------------- The process of loading a model is quite simple, and are based on the classes available on the *framed* package. .. Despite the SBML file path which contains the metabolic model itself, the user must provide a dictionary with the information of the parameters (vMax or enzyme identifier) which will be used to perform the strain optimization. .. If the *map* argument is not given, we assume that the vMax parameters associeted to each reaction has the follow identifier "vMax****". We assume that the vMax parameters associated to each reaction has the follow identifier "vMax****". :: from optimModels import load_kinetic_model model = load_kinetic_model('TinyModel_RHS.xml') Loading community models or stoichiometric models ------------------------------------------------- :: from framed.io.sbml import load_cbmodel model = load_cbmodel("Ec_iAF1260.xml", flavor="cobra") Loading GECKO models ----------------------- Please, to understand the GECKO models read the paper: Sánchez, Benjamín J., et al. *"Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints."* Molecular systems biology 13.8 (2017): 935. :: from geckopy import GeckoModel model = GeckoModel("single-pool")